MOTS‑c – 10mg

MOTS‑c is a synthetic peptide derived from a short open‑reading frame within mitochondrial DNA, making it distinct from traditional nuclear‑encoded peptides. It has become a major focus in modern research due to its relevance in cellular energy regulation, metabolic signalling, and stress‑response pathways.

As a mitochondrial‑derived peptide (MDP), MOTS‑c provides a unique tool for studying mitochondrial communication, metabolic homeostasis, and adaptive cellular responses in controlled laboratory environments. This peptide is supplied as a high‑purity lyophilised powder and is not approved for human or veterinary use.

Areas of Research Interest
Metabolic Signalling Pathways
Used in studies examining glucose utilisation, lipid regulation, and mitochondrial‑driven metabolic processes.

Exercise & Performance Models
Investigated in preclinical environments exploring peptide involvement in endurance, muscle adaptation, and exercise‑related biochemical responses.

Aging & Cellular Resilience Research
Included in research focusing on mitochondrial stress responses, longevity‑related pathways, and cellular protection mechanisms.

Oxidative Stress & Homeostasis
Explored in models studying antioxidant signalling, metabolic dysfunction, and mitochondrial communication.

These research areas highlight MOTS‑c as a key peptide for investigating mitochondrial biology and energy‑related pathways.

Technical Information
Chemical Name: Mitochondrial‑Derived Peptide MOTS‑c

Synonyms: MOTSc, Mitochondrial ORF of 12S rRNA type‑c

Molecular Formula: C₃₇₇H₆₄₀N₁₀₆O₁₂₆S

Molecular Weight: ~2171 g/mol

Sequence: Met‑Arg‑Trp‑Gln‑Glu‑Met‑Gly‑Tyr‑Ile‑Phe‑Tyr‑Pro‑Arg‑Lys‑Leu

CAS Number: 1465911‑04‑7

Classification: Mitochondrial‑derived peptide (MDP)

Storage Guidelines
Lyophilised peptide is stable at room temperature for short periods.

For long‑term storage, keep at –20°C or below.

After reconstitution, store at 2–8°C.

Stability depends on solvent and laboratory handling conditions.

Solubility
Soluble in sterile water and common aqueous laboratory buffers.

References (Research Context Only)
Lee et al. – Studies on metabolic homeostasis and mitochondrial signalling

Lu et al. – Investigations into adipose regulation and metabolic pathways

Shen & He – Reviews on MOTS‑c in aging and mitochondrial communication

(Full citations available upon request. Direct links removed for compliance.)

Compliance Notice
For laboratory research use only. Not for human or animal administration.